THE KIDNEY UNDER ATTACK

Saturday 18 September 2021 at the Maritim Hotel, Turtle Bay, Balaclava. Directions

***ISN’s endorsement*** *is for the promotion of education in general, therefore the specific content of the event/course is the responsibility of the organizer*. Find out more about the ISN through their website: http://www.theisn.org

Approved for 4 CPD points by the Medical Council of Mauritius

PROGRAMME SUMMARY

14.30 Registration

15.00 Introduction (Dr K Fagoonee and D Ip)

15.10 Looking at AKI with fresh eyes (Dr I Oozeerally, JNH)

15.55 Mechanisms of AKI viewed through the prism of SARS-COV-2 (Dr M Rughooputh, U of Mauritius)

16.40 Infectious Diseases: Old and new foes for the kidney (Dr D Nuckchady, VH)

17.25 Tea and coffee

18.00 Infection, inoculation and immunity (Dr D Ip, SSRNH)

18.45 When drugs damage the kidneys (Dr Y Gendoo, Nephron Ltd)

19.30 Concluding remarks (Dr Ruhooputh)

20.00 BUFFET DINNER

CATCH-UP VIDEOS OF THE FULL PROGRAMME

15.00-15.10 Introduction (Dr K Fagoonee First President and Dr D Ip, Current President)

15.10-15.55 Looking at AKI with fresh eyes (Dr I Oozeerally, Specialist in Nephrology, JNH)

Acute Kidney Injury (AKI) may be as old as humanity but only became a widely accepted and disseminated concept in the last decade. In Mauritius, AKI remains little understood and its devastating impact under-appreciated. This talk will discuss the definition(s) and epidemiology of AKI and its relationship with Chronic Kidney Disease (CKD), clinical features and management as well as its immediate and long term complications. A review of the relevant research and the development of electronic tools for the recognition and management of AKI will conclude the session.

15.55-16.40 Mechanisms of AKI viewed through the prism of SARS-COV-2 (Dr M Rughooputh, Specialist in Nephrology, University of Mauritius)

Abstract: Following on the first talk on AKI, the numerous causes and complex mechanisms of AKI with particular (but not exclusive) attention to acute tubular injury and its relationship to sepsis syndrome and cytokine storm will be discussed. Recent developments in laboratory and clinical research have improved our diagnosis and management of the different types of AKI. The COVID-19 pandemic illustrates the multi-system pathogenicity of the SARS-COV-2 virus. Its role in the causation of AKI will examined as well as the possible long term renal sequelae of COVID-19 infection.

16.40–17.25 Infectious Diseases: Old and new foes for the kidney (Dr D Nuckchady, Specialist in Infectious Diseases and Internal Medicine, VH)

Abstract: Looking away from diabetes and hypertension, this session will remind us of the enormous impact of acute and chronic infectious diseases on kidney health when viewed from a historical and global perspective. The pathogens range from bacteria, protozoa to viruses that have thrived in previous and present pandemics. In many parts of the world malaria, tuberculosis and viral hepatitis remain formidable enemies to public health and contribute to global kidney disease. What are the emerging threats? How do infectious diseases jump from the species barrier? Can we predict and even prevent future pandemics?

17.25 TEA AND COFFEE BREAK

18.00–18.45 Infection, inoculation and immunity (Dr D Ip, Specialist in Nephrology and Internal Medicine, SSRNH)

Abstract: A local case report of a patient with nephrotic syndrome and hypertension and its diagnostic workup will presented. The clinical course with marked improvement with antiviral agent, a subsequent relapse with COVID-19 and the management dilemmas will be discussed. There will be a review of the nephrotic syndrome, various forms of associated kidney disease associated with hepatitis B and its management as well as vaccine associated kidney disease. In particular, the relationship of various COVID-19 vaccines as a trigger de novo and relapses of immunological kidney diseases will be discussed.

18.45-19.30 When drugs damage the kidneys (Dr Y Gendoo, Specialist in Nephrology, Nephron Ltd)

Abstract: Drugs are a relatively common cause of acute kidney injury (AKI), especially in hospitalized patients who are exposed to numerous agents. Some drugs are inherently nephrotoxic but this session will consider physiological processes like drug transport and metabolism that mediate that toxicity. Acute tubular injury (already discussed in an earlier session) and acute interstitial nephritis are the most common causes of drug related AKI but other mechanisms have been described both with well established drugs as well with the latest biological agents used in the field of cancer amongst others.